1.What is milsaperidone used for?

Milsaperidone is used to treat schizophrenia and acute manic or mixed episodes in adults with bipolar I disorder.

2.When was milsaperidone approved?

The milsaperidone FDA approval occurred on February 20, 2026.

3.What class of drug is milsaperidone?

It belongs to the atypical antipsychotic class of medications.

4.How does milsaperidone work?

It works by blocking dopamine D2, serotonin 5-HT2A, and alpha-1 adrenergic receptors in the brain.

5.What are the common side effects?

Common side effects include dizziness, drowsiness, fatigue, dry mouth, and weight gain.

6.Can milsaperidone interact with other medications?

Yes, it may interact with CYP3A4 inhibitors, CYP inducers, CNS depressants, and QT-prolonging medications.

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